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Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector
Engineered DNA-binding proteins that manipulate the human genome and transcriptome have enabled rapid advances in biomedical research. In particular, the RNA-guided CRISPR/Cas9 system has recently been engineered to create site-specific double-strand breaks for genome editing or to direct targeted t...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231726/ https://ncbi.nlm.nih.gov/pubmed/25122746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku749 |
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