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A CRISPR/Cas9-Based System for Reprogramming Cell Lineage Specification
Gene activation by the CRISPR/Cas9 system has the potential to enable new approaches to science and medicine, but the technology must be enhanced to robustly control cell behavior. We show that the fusion of two transactivation domains to Cas9 dramatically enhances gene activation to a level that is...
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| Pubblicato in: | Stem Cell Reports |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4264059/ https://ncbi.nlm.nih.gov/pubmed/25448066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.09.013 |
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