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Engineering Synthetic TALE and CRISPR/Cas9 Transcription Factors for Regulating Gene Expression

Engineered DNA-binding proteins that can be targeted to specific sites in the genome to manipulate gene expression have enabled many advances in biomedical research. This includes generating tools to study fundamental aspects of gene regulation and the development of a new class of gene therapies th...

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Bibliografische gegevens
Hoofdauteurs: Kabadi, Ami M., Gersbach, Charles A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175060/
https://ncbi.nlm.nih.gov/pubmed/25010559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2014.06.014
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