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Engineering Synthetic TALE and CRISPR/Cas9 Transcription Factors for Regulating Gene Expression
Engineered DNA-binding proteins that can be targeted to specific sites in the genome to manipulate gene expression have enabled many advances in biomedical research. This includes generating tools to study fundamental aspects of gene regulation and the development of a new class of gene therapies th...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4175060/ https://ncbi.nlm.nih.gov/pubmed/25010559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2014.06.014 |
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