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Engineering Synthetic TALE and CRISPR/Cas9 Transcription Factors for Regulating Gene Expression

Engineered DNA-binding proteins that can be targeted to specific sites in the genome to manipulate gene expression have enabled many advances in biomedical research. This includes generating tools to study fundamental aspects of gene regulation and the development of a new class of gene therapies th...

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Detalles Bibliográficos
Main Authors: Kabadi, Ami M., Gersbach, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175060/
https://ncbi.nlm.nih.gov/pubmed/25010559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2014.06.014
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