Highly active zinc-finger nucleases by extended modular assembly

Zinc-finger nucleases (ZFNs) are important tools for genome engineering. Despite intense interest by many academic groups, the lack of robust noncommercial methods has hindered their widespread use. The modular assembly (MA) of ZFNs from publicly available one-finger archives provides a rapid method...

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Detalles Bibliográficos
Main Authors: Bhakta, Mital S., Henry, Isabelle M., Ousterout, David G., Das, Kumitaa Theva, Lockwood, Sarah H., Meckler, Joshua F., Wallen, Mark C., Zykovich, Artem, Yu, Yawei, Leo, Heather, Xu, Lifeng, Gersbach, Charles A., Segal, David J.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Method
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589541/
https://ncbi.nlm.nih.gov/pubmed/23222846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.143693.112
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