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Evaluation and application of modularly assembled zinc-finger nucleases in zebrafish
Zinc-finger nucleases (ZFNs) allow targeted gene inactivation in a wide range of model organisms. However, construction of target-specific ZFNs is technically challenging. Here, we evaluate a straightforward modular assembly-based approach for ZFN construction and gene inactivation in zebrafish. Fro...
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| Hauptverfasser: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Company of Biologists
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177320/ https://ncbi.nlm.nih.gov/pubmed/21937602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.066779 |
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