Cargando...
Targeted gene inactivation in zebrafish using engineered zinc finger nucleases
In most vertebrate model systems direct genomic manipulation at a specific locus is still not feasible. Zinc finger nucleases (ZFNs) provide a system to introduce genomic lesions at a specific site in vertebrate cell lines1-3. Here, we adapt this technology to create targeted mutations in the zebraf...
Guardado en:
| Autores principales: | , , , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2502069/ https://ncbi.nlm.nih.gov/pubmed/18500337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt1398 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|