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An optimized two-finger archive for ZFN-mediated gene targeting
The widespread use of zinc finger nucleases (ZFNs) for genome engineering is hampered by the fact that only a subset of sequences can be efficiently recognized using published finger archives. We describe a set of validated two-finger modules that complement existing finger archives and expand the r...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443678/ https://ncbi.nlm.nih.gov/pubmed/22543349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1994 |
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