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ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites
BACKGROUND: Zinc Finger Nucleases (ZFNs) are man-made restriction enzymes useful for manipulating genomes by cleaving target DNA sequences. ZFNs allow therapeutic gene correction or creation of genetically modified model organisms. ZFN specificity is not absolute; therefore, it is essential to selec...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
BioMed Central
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113941/ https://ncbi.nlm.nih.gov/pubmed/21569489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-152 |
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