Advances in MicroRNAs: Implications for Gene Therapists

Por MARQUEZ, REBECCA T., McCAFFREY, ANTON P.
Publicado em 2008

MicroRNA-21 is upregulated during the proliferative phase of liver regeneration, targets Pellino-1, and inhibits NF-κB signaling

Por Marquez, Rebecca T., Wendlandt, Erik, Galle, Courtney Searcey, Keck, Kathy, McCaffrey, Anton P.
Publicado em 2010

ZFN-Site searches genomes for zinc finger nuclease target sites and off-target sites

Por Cradick, Thomas J, Ambrosini, Giovanna, Iseli, Christian, Bucher, Philipp, McCaffrey, Anton P
Publicado em 2011

Zinc-finger Nucleases as a Novel Therapeutic Strategy for Targeting Hepatitis B Virus DNAs

Por Cradick, Thomas J, Keck, Kathy, Bradshaw, Shannon, Jamieson, Andrew C, McCaffrey, Anton P
Publicado em 2010

5′ Unlocked Nucleic Acid Modification Improves siRNA Targeting

Por Snead, Nicholas M, Escamilla-Powers, Julie R, Rossi, John J, McCaffrey, Anton P
Publicado em 2013

Identifying Functional MicroRNAs in Macrophages with Polarized Phenotypes

Por Graff, Joel W., Dickson, Anne M., Clay, Gwendolyn, McCaffrey, Anton P., Wilson, Mary E.
Publicado em 2012

The role of MicroRNAs miR-200b and miR-200c in TLR4 signaling and NF-κB activation

Por Wendlandt, Erik B, Graff, Joel W, Gioannini, Theresa L, McCaffrey, Anton P, Wilson, Mary E
Publicado em 2012

In vitro RNA SELEX for the generation of chemically-optimized therapeutic RNA drugs

Por Urak, Kevin T., Shore, Sabrina, Rockey, William M., Chen, Shi-Jie, McCaffrey, Anton P., Giangrande, Paloma H.
Publicado no Methods (2016)

Rational Design Leads to More Potent RNA Interference Against Hepatitis B Virus: Factors Effecting Silencing Efficiency

Por Keck, Kathy, Volper, Esther M, Spengler, Ryan M, Long, Dang D, Chan, Chi Y, Ding, Ye, McCaffrey, Anton P
Publicado em 2008

Small RNA Library Preparation Method for Next-Generation Sequencing Using Chemical Modifications to Prevent Adapter Dimer Formation

Por Shore, Sabrina, Henderson, Jordana M., Lebedev, Alexandre, Salcedo, Michelle P., Zon, Gerald, McCaffrey, Anton P., Paul, Natasha, Hogrefe, Richard I.
Publicado no PLoS One (2016)

Biliverdin Inhibits Hepatitis C Virus NS3/4A Protease Activity: Mechanism for the Antiviral Effects of Heme Oxygenase?

Por Zhu, Zhaowen, Wilson, Anne T., Luxon, Bruce A., Brown, Kyle E., Mathahs, M. Meleah, Bandyopadhyay, Sarmistha, McCaffrey, Anton P., Schmidt, Warren N.
Publicado em 2010

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects

Por Ramirez, Cherie L., Certo, Michael T., Mussolino, Claudio, Goodwin, Mathew J., Cradick, Thomas J., McCaffrey, Anton P., Cathomen, Toni, Scharenberg, Andrew M., Joung, J. Keith
Publicado em 2012

Hepatitis C Virus Infection and Hepatic Stellate Cell Activation Downregulate miR-29: miR-29 Overexpression Reduces Hepatitis C Viral Abundance in Culture

Por Bandyopadhyay, Sarmistha, Friedman, Robin C., Marquez, Rebecca T., Keck, Kathy, Kong, Benjamin, Icardi, Michael S., Brown, Kyle E., Burge, Christopher B., Schmidt, Warren N., Wang, Yulei, McCaffrey, Anton P.
Publicado em 2011

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

Por Dassie, Justin P, Liu, Xiu-ying, Thomas, Gregory S, Whitaker, Ryan M, Thiel, Kristina W, Stockdale, Katie R, Meyerholz, David K, McCaffrey, Anton P, McNamara, James O, Giangrande, Paloma H
Publicado em 2009

Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification

Por Vaidyanathan, Sriram, Azizian, Krist T., Haque, A.K.M. Ashiqul, Henderson, Jordana M., Hendel, Ayal, Shore, Sabrina, Antony, Justin S., Hogrefe, Richard I., Kormann, Michael S.D., Porteus, Matthew H., McCaffrey, Anton P.
Publicado no Mol Ther Nucleic Acids (2018)