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In vitro RNA SELEX for the generation of chemically-optimized therapeutic RNA drugs
Aptamers are single-stranded DNA or RNA oligonucleotides that can bind with exquisitely high affinity and specificity to target molecules and are thus often referred to as ‘nucleic acid’ antibodies. Oligonucleotide aptamers are derived through a process of directed chemical evolution called SELEX (S...
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| Publicado no: | Methods |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4921298/ https://ncbi.nlm.nih.gov/pubmed/26972786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2016.03.003 |
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