Nucleotide Bias Observed with a Short SELEX RNA Aptamer Library

Systematic evolution of ligands by exponential enrichment (SELEX) is a powerful in vitro selection process used for over 2 decades to identify oligonucleotide sequences (aptamers) with desired properties (usually high affinity for a protein target) from randomized nucleic acid libraries. In the case...

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Détails bibliographiques
Auteurs principaux: Thiel, William H., Bair, Thomas, Thiel, Kristina Wyatt, Dassie, Justin P., Rockey, William M., Howell, Craig A., Liu, Xiuying Y., Dupuy, Adam J., Huang, Lingyan, Owczarzy, Richard, Behlke, Mark A., McNamara, James O., Giangrande, Paloma H.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2011
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198618/
https://ncbi.nlm.nih.gov/pubmed/21793789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2011.0288
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