Nucleotide Bias Observed with a Short SELEX RNA Aptamer Library

Systematic evolution of ligands by exponential enrichment (SELEX) is a powerful in vitro selection process used for over 2 decades to identify oligonucleotide sequences (aptamers) with desired properties (usually high affinity for a protein target) from randomized nucleic acid libraries. In the case...

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Detalhes bibliográficos
Main Authors: Thiel, William H., Bair, Thomas, Thiel, Kristina Wyatt, Dassie, Justin P., Rockey, William M., Howell, Craig A., Liu, Xiuying Y., Dupuy, Adam J., Huang, Lingyan, Owczarzy, Richard, Behlke, Mark A., McNamara, James O., Giangrande, Paloma H.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198618/
https://ncbi.nlm.nih.gov/pubmed/21793789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2011.0288
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