Nucleotide Bias Observed with a Short SELEX RNA Aptamer Library

Systematic evolution of ligands by exponential enrichment (SELEX) is a powerful in vitro selection process used for over 2 decades to identify oligonucleotide sequences (aptamers) with desired properties (usually high affinity for a protein target) from randomized nucleic acid libraries. In the case...

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Hlavní autoři: Thiel, William H., Bair, Thomas, Thiel, Kristina Wyatt, Dassie, Justin P., Rockey, William M., Howell, Craig A., Liu, Xiuying Y., Dupuy, Adam J., Huang, Lingyan, Owczarzy, Richard, Behlke, Mark A., McNamara, James O., Giangrande, Paloma H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2011
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198618/
https://ncbi.nlm.nih.gov/pubmed/21793789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2011.0288
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