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Intracellular delivery of RNA-based therapeutics using aptamers

The clinical potential of siRNAs for silencing genes critical to disease progression is clear, but a fail-proof method for delivering siRNAs to the cytoplasm of diseased tissues or cells has yet to be identified. A variety of delivery approaches have been explored to directly or indirectly couple si...

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Detalhes bibliográficos
Main Authors: Thiel, Kristina W, Giangrande, Paloma H
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106310/
https://ncbi.nlm.nih.gov/pubmed/21643487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/tde.10.61
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