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Intracellular delivery of RNA-based therapeutics using aptamers
The clinical potential of siRNAs for silencing genes critical to disease progression is clear, but a fail-proof method for delivering siRNAs to the cytoplasm of diseased tissues or cells has yet to be identified. A variety of delivery approaches have been explored to directly or indirectly couple si...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3106310/ https://ncbi.nlm.nih.gov/pubmed/21643487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/tde.10.61 |
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