Using defined finger–finger interfaces as units of assembly for constructing zinc-finger nucleases

Zinc-finger nucleases (ZFNs) have been used for genome engineering in a wide variety of organisms; however, it remains challenging to design effective ZFNs for many genomic sequences using publicly available zinc-finger modules. This limitation is in part because of potential finger–finger incompati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhu, Cong, Gupta, Ankit, Hall, Victoria L., Rayla, Amy L., Christensen, Ryan G., Dake, Benjamin, Lakshmanan, Abirami, Kuperwasser, Charlotte, Stormo, Gary D., Wolfe, Scot A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2013
Pynciau:
Nucleic Acid Enzymes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575815/
https://ncbi.nlm.nih.gov/pubmed/23303772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1357
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg