Highly active zinc-finger nucleases by extended modular assembly

Zinc-finger nucleases (ZFNs) are important tools for genome engineering. Despite intense interest by many academic groups, the lack of robust noncommercial methods has hindered their widespread use. The modular assembly (MA) of ZFNs from publicly available one-finger archives provides a rapid method...

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Hlavní autoři: Bhakta, Mital S., Henry, Isabelle M., Ousterout, David G., Das, Kumitaa Theva, Lockwood, Sarah H., Meckler, Joshua F., Wallen, Mark C., Zykovich, Artem, Yu, Yawei, Leo, Heather, Xu, Lifeng, Gersbach, Charles A., Segal, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2013
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Method
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589541/
https://ncbi.nlm.nih.gov/pubmed/23222846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.143693.112
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