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Adding Fingers To An Engineered Zinc Finger Nuclease Can Reduce Activity
Zinc finger nucleases (ZFN) have been used to direct precise modifications to the genetic information in living cells at high efficiency. An important consideration in the design of ZFNs is the number of zinc fingers that are required for efficient and specific cleavage. We examined dimeric ZFNs com...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110833/ https://ncbi.nlm.nih.gov/pubmed/21528840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200393g |
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