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Genome Engineering With Zinc-Finger Nucleases
Zinc-finger nucleases (ZFNs) are targetable DNA cleavage reagents that have been adopted as gene-targeting tools. ZFN-induced double-strand breaks are subject to cellular DNA repair processes that lead to both targeted mutagenesis and targeted gene replacement at remarkably high frequencies. This ar...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3176093/ https://ncbi.nlm.nih.gov/pubmed/21828278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.131433 |
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