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Genome Engineering With Zinc-Finger Nucleases

Zinc-finger nucleases (ZFNs) are targetable DNA cleavage reagents that have been adopted as gene-targeting tools. ZFN-induced double-strand breaks are subject to cellular DNA repair processes that lead to both targeted mutagenesis and targeted gene replacement at remarkably high frequencies. This ar...

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Bibliografske podrobnosti
Glavni avtor: Carroll, Dana
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176093/
https://ncbi.nlm.nih.gov/pubmed/21828278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.131433
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