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Transversions have larger regulatory effects than transitions

BACKGROUND: Transversions (Tv’s) are more likely to alter the amino acid sequence of proteins than transitions (Ts’s), and local deviations in the Ts:Tv ratio are indicative of evolutionary selection on genes. Whether the two different types of mutations have different effects in non-protein-coding...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Guo, Cong, McDowell, Ian C., Nodzenski, Michael, Scholtens, Denise M., Allen, Andrew S., Lowe, William L., Reddy, Timothy E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438547/
https://ncbi.nlm.nih.gov/pubmed/28525990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-3785-4
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