Bayesian estimation of genetic regulatory effects in high-throughput reporter assays

MOTIVATION: High-throughput reporter assays dramatically improve our ability to assign function to noncoding genetic variants, by measuring allelic effects on gene expression in the controlled setting of a reporter gene. Unlike genetic association tests, such assays are not confounded by linkage dis...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Majoros, William H, Kim, Young-Sook, Barrera, Alejandro, Li, Fan, Wang, Xingyan, Cunningham, Sarah J, Johnson, Graham D, Guo, Cong, Lowe, William L, Scholtens, Denise M, Hayes, M Geoffrey, Reddy, Timothy E, Allen, Andrew S
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Original Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7999138/
https://ncbi.nlm.nih.gov/pubmed/31368479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz545
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