Correcting signal biases and detecting regulatory elements in STARR-seq data

High-throughput reporter assays such as self-transcribing active regulatory region sequencing (STARR-seq) have made it possible to measure regulatory element activity across the entire human genome at once. The resulting data, however, present substantial analytical challenges. Here, we identify tec...

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Vydáno v:Genome Res
Hlavní autoři: Kim, Young-Sook, Johnson, Graham D., Seo, Jungkyun, Barrera, Alejandro, Cowart, Thomas N., Majoros, William H., Ochoa, Alejandro, Allen, Andrew S., Reddy, Timothy E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2021
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Method
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092017/
https://ncbi.nlm.nih.gov/pubmed/33722938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.269209.120
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