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STARRPeaker: uniform processing and accurate identification of STARR-seq active regions

STARR-seq technology has employed progressively more complex genomic libraries and increased sequencing depths. An issue with the increased complexity and depth is that the coverage in STARR-seq experiments is non-uniform, overdispersed, and often confounded by sequencing biases, such as GC content....

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Lee, Donghoon, Shi, Manman, Moran, Jennifer, Wall, Martha, Zhang, Jing, Liu, Jason, Fitzgerald, Dominic, Kyono, Yasuhiro, Ma, Lijia, White, Kevin P., Gerstein, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722316/
https://ncbi.nlm.nih.gov/pubmed/33292397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02194-x
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