PennSeq: accurate isoform-specific gene expression quantification in RNA-Seq by modeling non-uniform read distribution

Correctly estimating isoform-specific gene expression is important for understanding complicated biological mechanisms and for mapping disease susceptibility genes. However, estimating isoform-specific gene expression is challenging because various biases present in RNA-Seq (RNA sequencing) data com...

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Detalles Bibliográficos
Main Authors: Hu, Yu, Liu, Yichuan, Mao, Xianyun, Jia, Cheng, Ferguson, Jane F., Xue, Chenyi, Reilly, Muredach P., Li, Hongzhe, Li, Mingyao
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
Assuntos:
Methods Online
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919567/
https://ncbi.nlm.nih.gov/pubmed/24362841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1304
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