Human genome-wide measurement of drug-responsive regulatory activity

Environmental stimuli commonly act via changes in gene regulation. Human-genome-scale assays to measure such responses are indirect or require knowledge of the transcription factors (TFs) involved. Here, we present the use of human genome-wide high-throughput reporter assays to measure environmental...

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I publikationen:Nat Commun
Huvudupphovsmän: Johnson, Graham D., Barrera, Alejandro, McDowell, Ian C., D’Ippolito, Anthony M., Majoros, William H., Vockley, Christopher M., Wang, Xingyan, Allen, Andrew S., Reddy, Timothy E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303339/
https://ncbi.nlm.nih.gov/pubmed/30575722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07607-x
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