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Are Nonsynonymous Transversions Generally More Deleterious than Nonsynonymous Transitions?

It has been suggested that, due to the structure of the genetic code, nonsynonymous transitions are less likely than transversions to cause radical changes in amino acid physicochemical properties so are on average less deleterious. This view was supported by some but not all mutagenesis experiments...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Zou, Zhengting, Zhang, Jianzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783172/
https://ncbi.nlm.nih.gov/pubmed/32805043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msaa200
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