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Are Nonsynonymous Transversions Generally More Deleterious than Nonsynonymous Transitions?

It has been suggested that, due to the structure of the genetic code, nonsynonymous transitions are less likely than transversions to cause radical changes in amino acid physicochemical properties so are on average less deleterious. This view was supported by some but not all mutagenesis experiments...

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Bibliografiska uppgifter
I publikationen:Mol Biol Evol
Huvudupphovsmän: Zou, Zhengting, Zhang, Jianzhi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783172/
https://ncbi.nlm.nih.gov/pubmed/32805043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msaa200
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