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Are Nonsynonymous Transversions Generally More Deleterious than Nonsynonymous Transitions?

It has been suggested that, due to the structure of the genetic code, nonsynonymous transitions are less likely than transversions to cause radical changes in amino acid physicochemical properties so are on average less deleterious. This view was supported by some but not all mutagenesis experiments...

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Detaylı Bibliyografya
Yayımlandı:Mol Biol Evol
Asıl Yazarlar: Zou, Zhengting, Zhang, Jianzhi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7783172/
https://ncbi.nlm.nih.gov/pubmed/32805043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msaa200
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