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Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism
Genome-wide association studies (GWAS) have consistently implicated noncoding variation within the TCF7L2 locus with type 2 diabetes (T2D) risk. While this locus represents the strongest genetic determinant for T2D risk in humans, it remains unclear how these noncoding variants affect disease etiolo...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166827/ https://ncbi.nlm.nih.gov/pubmed/21673050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.123745.111 |
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