Mechanism of Cell Cycle Entry Mediated by the Intrinsically Disordered Protein, p27(Kip1)

Por Ou, Li, Waddell, M. Brett, Kriwacki, Richard W.
Publicado em 2012

Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1

Por Souphron, Judith, Waddell, M. Brett, Paydar, Amir, Tokgöz-Gromley, Zeynep, Roussel, Martine F., Schulman, Brenda A.
Publicado em 2008

A short linear motif in BNIP3L (NIX) mediates mitochondrial clearance in reticulocytes

Por Zhang, Ji, Loyd, Melanie R., Randall, Mindy S., Waddell, M. Brett, Kriwacki, Richard W., Ney, Paul A.
Publicado em 2012

Architecture of the Bacteriophage T4 Activator MotA/Promoter DNA Interaction during Sigma Appropriation

Por Hsieh, Meng-Lun, James, Tamara D., Knipling, Leslie, Waddell, M. Brett, White, Stephen, Hinton, Deborah M.
Publicado em 2013

The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase

Por Yun, Mi-Kyung, Hoagland, Daniel, Kumar, Gyanendra, Waddell, M. Brett, Rock, Charles O., Lee, Richard E., White, Stephen W.
Publicado no Bioorg Med Chem (2014)

Design, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 Interaction

Por Pettersson, Mariell, Quant, Maria, Min, Jaeki, Iconaru, Luigi, Kriwacki, Richard W., Waddell, M. Brett, Guy, R. Kiplin, Luthman, Kristina, Grøtli, Morten
Publicado no PLoS One (2015)

The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-α/β-induced ubiquitin-like protein

Por Zhao, Chen, Beaudenon, Sylvie L., Kelley, Melissa L., Waddell, M. Brett, Yuan, Weiming, Schulman, Brenda A., Huibregtse, Jon M., Krug, Robert M.
Publicado em 2004

Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase: Crystal structures reveal the catalytic mechanism of DHPS and the structural basis of sulfa drug action and resista...

Por Yun, Mi-Kyung, Wu, Yinan, Li, Zhenmei, Zhao, Ying, Waddell, M. Brett, Ferreira, Antonio M., Lee, Richard E., Bashford, Donald, White, Stephen W.
Publicado em 2012

Structure of a SUMO-binding-motif mimic bound to Smt3p–Ubc9p: conservation of a noncovalent Ubiquitin-like protein–E2 complex as a platform for selective interactions within a SUMO...

Por Duda, David M., van Waardenburg, Robert C. A. M., Borg, Laura A., McGarity, Sierra, Nourse, Amanda, Waddell, M. Brett, Bjornsti, Mary-Ann, Schulman, Brenda A.
Publicado em 2007

Structure of a Glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface

Por Duda, David M., Olszewski, Jennifer L., Tron, Adriana E., Hammel, Michal, Lambert, Lester J., Waddell, M. Brett, Mittag, Tanja, DeCaprio, James A., Schulman, Brenda A.
Publicado em 2012

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases

Por Zhuang, Min, Calabrese, Matthew F., Liu, Jiang, Waddell, M. Brett, Nourse, Amanda, Hammel, Michal, Miller, Darcie J., Walden, Helen, Duda, David M., Seyedin, Steven N., Hoggard, Timothy, Harper, J. Wade, White, Kevin P., Schulman, Brenda A.
Publicado em 2009

MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression

Por Paugh, Steven W., Coss, David R., Bao, Ju, Laudermilk, Lucas T., Grace, Christy R., Ferreira, Antonio M., Waddell, M. Brett, Ridout, Granger, Naeve, Deanna, Leuze, Michael, LoCascio, Philip F., Panetta, John C., Wilkinson, Mark R., Pui, Ching-Hon, Naeve, Clayton W., Uberbacher, Edward C., Bonten, Erik J., Evans, William E.
Publicado no PLoS Comput Biol (2016)