טוען...
The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK) is an essential enzyme in the microbial folate biosynthetic pathway. This pathway has proven to be an excellent target for antimicrobial development, but widespread resistance to common therapeutics including the sulfa drugs has stimulated i...
שמור ב:
| הוצא לאור ב: | Bioorg Med Chem |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269157/ https://ncbi.nlm.nih.gov/pubmed/24613625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.02.022 |
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