Llwytho...

Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1

[Image: see text] Post-translational covalent modification by ubiquitin and ubiquitin-like proteins (UBLs) is a major eukaryotic mechanism for regulating protein function. In general, each UBL has its own E1 that serves as the entry point for a cascade. The E1 first binds the UBL and catalyzes adeny...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Souphron, Judith, Waddell, M. Brett, Paydar, Amir, Tokgöz-Gromley, Zeynep, Roussel, Martine F., Schulman, Brenda A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2008
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587436/
https://ncbi.nlm.nih.gov/pubmed/18652489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800604c
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!