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Mechanism of Cell Cycle Entry Mediated by the Intrinsically Disordered Protein, p27(Kip1)
p27(Kip1) (p27), a prototypical intrinsically disordered protein (IDP), regulates eukaryotic cell division through interactions with cyclin-dependent kinase (Cdk)/cyclin complexes. The activity, stability and sub-cellular localization of p27 are regulated by phosphorylation. We illustrate how p27 in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3331940/ https://ncbi.nlm.nih.gov/pubmed/22276948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200487h |
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