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Mechanism of Cell Cycle Entry Mediated by the Intrinsically Disordered Protein, p27(Kip1)

p27(Kip1) (p27), a prototypical intrinsically disordered protein (IDP), regulates eukaryotic cell division through interactions with cyclin-dependent kinase (Cdk)/cyclin complexes. The activity, stability and sub-cellular localization of p27 are regulated by phosphorylation. We illustrate how p27 in...

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Autors principals: Ou, Li, Waddell, M. Brett, Kriwacki, Richard W.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331940/
https://ncbi.nlm.nih.gov/pubmed/22276948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200487h
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