Ureadepsipeptides as ClpP Activators

Acyldepsipeptides are a unique class of antibiotics that act via allosterically dysregulated activation of the bacterial caseinolytic protease (ClpP). The ability of ClpP activators to kill non-growing bacteria represents a new opportunity to combat deep-seated biofilm infections. However, the acyl...

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發表在:ACS Infect Dis
Main Authors: Griffith, Elizabeth C., Zhao, Ying, Singh, Aman P., Conlon, Brian P., Tangallapally, Rajendra, Shadrick, William R., Liu, Jiuyu, Wallace, Miranda J., Yang, Lei, Elmore, John M., Li, Yong, Zheng, Zhong, Miller, Darcie J., Cheramie, Martin N., Lee, Robin B., LaFleur, Michael D., Lewis, Kim, Lee, Richard E.
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916429/
https://ncbi.nlm.nih.gov/pubmed/31588734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00245
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