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Identification and Analysis of Inhibitors Targeting the Hepatitis C Virus NS3 Helicase
This chapter describes two types of FRET-based fluorescence assays that can be used to identify and analyze compounds that inhibit the helicase encoded by the hepatitis C virus (HCV). Both assays use a fluorescently labeled DNA or RNA oligonucleotide to monitor helicase-catalyzed strand separation,...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3571682/ https://ncbi.nlm.nih.gov/pubmed/22713333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-396546-2.00021-8 |
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