Identification of Hydroxyanthraquinones as Novel Inhibitors of Hepatitis C Virus NS3 Helicase

Hepatitis C virus (HCV) is an important etiological agent of severe liver diseases, including cirrhosis and hepatocellular carcinoma. The HCV genome encodes nonstructural protein 3 (NS3) helicase, which is a potential anti-HCV drug target because its enzymatic activity is essential for viral replica...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Furuta, Atsushi, Tsubuki, Masayoshi, Endoh, Miduki, Miyamoto, Tatsuki, Tanaka, Junichi, Abdus Salam, Kazi, Akimitsu, Nobuyoshi, Tani, Hidenori, Yamashita, Atsuya, Moriishi, Kohji, Nakakoshi, Masamichi, Sekiguchi, Yuji, Tsuneda, Satoshi, Noda, Naohiro
Format: Artigo
Langue:Inglês
Publié: MDPI 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581254/
https://ncbi.nlm.nih.gov/pubmed/26262613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160818439
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