Inhibition of Hepatitis C Virus Replication and Viral Helicase by Ethyl Acetate Extract of the Marine Feather Star Alloeocomatella polycladia

Hepatitis C virus (HCV) is a causative agent of acute and chronic hepatitis, leading to the development of hepatic cirrhosis and hepatocellular carcinoma. We prepared extracts from 61 marine organisms and screened them by an in vitro fluorescence assay targeting the viral helicase (NS3), which plays...

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Autors principals: Yamashita, Atsuya, Salam, Kazi Abdus, Furuta, Atsushi, Matsuda, Yasuyoshi, Fujita, Osamu, Tani, Hidenori, Fujita, Yoshihisa, Fujimoto, Yuusuke, Ikeda, Masanori, Kato, Nobuyuki, Sakamoto, Naoya, Maekawa, Shinya, Enomoto, Nobuyuki, Nakakoshi, Masamichi, Tsubuki, Masayoshi, Sekiguchi, Yuji, Tsuneda, Satoshi, Akimitsu, Nobuyoshi, Noda, Naohiro, Tanaka, Junichi, Moriishi, Kohji
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366673/
https://ncbi.nlm.nih.gov/pubmed/22690141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md10040744
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