Inhibition of Both Protease and Helicase Activities of Hepatitis C Virus NS3 by an Ethyl Acetate Extract of Marine Sponge Amphimedon sp

Combination therapy with ribavirin, interferon, and viral protease inhibitors could be expected to elicit a high level of sustained virologic response in patients infected with hepatitis C virus (HCV). However, several severe side effects of this combination therapy have been encountered in clinical...

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Hauptverfasser: Fujimoto, Yuusuke, Salam, Kazi Abdus, Furuta, Atsushi, Matsuda, Yasuyoshi, Fujita, Osamu, Tani, Hidenori, Ikeda, Masanori, Kato, Nobuyuki, Sakamoto, Naoya, Maekawa, Shinya, Enomoto, Nobuyuki, de Voogd, Nicole J., Nakakoshi, Masamichi, Tsubuki, Masayoshi, Sekiguchi, Yuji, Tsuneda, Satoshi, Akimitsu, Nobuyoshi, Noda, Naohiro, Yamashita, Atsuya, Tanaka, Junichi, Moriishi, Kohji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492463/
https://ncbi.nlm.nih.gov/pubmed/23144928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048685
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