Room-Temperature, Copper-Free Sonogashira Reactions Facilitated by Air-Stable, Monoligated Precatalyst [DTBNpP] Pd(crotyl)Cl

by Pohida, Katherine, Maloney, David J., Mott, Bryan T., Rai, Ganesha
Published in ACS Omega (2018)

Discovery of Novel Liver-Stage Antimalarials through Quantum Similarity

by Sullivan, David J., Liu, Yi, Mott, Bryan T., Kaludov, Nikola, Martinov, Martin N.
Published in PLoS One (2015)

Comparison of Raltegravir and Elvitagravir on HIV-1 Integrase Catalytic Reactions and on a Series of Drug-Resistant Integrase Mutants

by Marinello, Jessica, Marchand, Christophe, Mott, Bryan, Bain, Anjali, Thomas, Craig J., Pommier, Yves
Published 2008

An Artemisinin-Derived Dimer Has Highly Potent Anti-Cytomegalovirus (CMV) and Anti-Cancer Activities

by He, Ran, Mott, Bryan T., Rosenthal, Andrew S., Genna, Douglas T., Posner, Gary H., Arav-Boger, Ravit
Published 2011

Unique and Highly Selective Anticytomegalovirus Activities of Artemisinin-Derived Dimer Diphenyl Phosphate Stem from Combination of Dimer Unit and a Diphenyl Phosphate Moiety

by He, Ran, Forman, Michael, Mott, Bryan T., Venkatadri, Rajkumar, Posner, Gary H., Arav-Boger, Ravit
Published 2013

Malaria-Infected Mice Are Cured by a Single Low Dose of a New Silylamide Trioxane Plus Mefloquine

by Woodard, Lauren E., Mott, Bryan T., Singhal, Vandana, Kumar, Nirbhay, Shapiro, Theresa A., Posner, Gary H.
Published 2009

Comparison of Bioluminescent Kinase Assays Using Substrate Depletion and Product Formation

by Tanega, Cordelle, Shen, Min, Mott, Bryan T., Thomas, Craig J., MacArthur, Ryan, Inglese, James, Auld, Douglas S.
Published 2009

Synthesis and Antimalarial Efficacy of Two-Carbon Linked, Artemisinin-Derived, Trioxane Dimers in Combination with Known Antimalarial Drugs

by Mott, Bryan T., Tripathi, Abhai, Siegler, Maxime A., Moore, Cathy D., Sullivan, David J., Posner, Gary H.
Published 2013

Drug resistant integrase mutants cause aberrant HIV integrations

by Varadarajan, Janani, McWilliams, Mary Jane, Mott, Bryan T., Thomas, Craig J., Smith, Steven J., Hughes, Stephen H.
Published in Retrovirology (2016)

Artemisinin-Derived Dimer Diphenyl Phosphate Is an Irreversible Inhibitor of Human Cytomegalovirus Replication

by He, Ran, Park, Kyoungsook, Cai, Hongyi, Kapoor, Arun, Forman, Michael, Mott, Bryan, Posner, Gary H., Arav-Boger, Ravit
Published 2012

High throughput screen identifies cyclic nucleotide analogs that inhibit Prostatic acid phosphatase

by McCoy, Eric S., Lea, Wendy A., Mott, Bryan T., Maloney, David J., Jadhav, Ajit, Simeonov, Anton, Zylka, Mark J.
Published 2012

Artemisinin-Derived Dimer Phosphate Esters as Potent Anti-Cytomegalovirus (Anti-CMV) and Anti-Cancer Agents: A Structure-Activity Study

by Mott, Bryan T., He, Ran, Chen, Xiaochun, Fox, Jennifer M., Civin, Curt I., Arav-Boger, Ravit, Posner, Gary H.
Published 2013

Thiazole, Oxadiazole, and Carboxamide Derivatives of Artemisinin are Highly Selective and Potent Inhibitors of Toxoplasma gondii

by Hencken, Christopher P., Jones-Brando, Lorraine, Bordón, Claudia, Stohler, Remo, Mott, Bryan T., Yolken, Robert, Posner, Gary H., Woodard, Lauren E.
Published 2010

The Survival Times Of Malaria-Infected Mice Are Prolonged More By Several New Two-Carbon-Linked Artemisinin-Derived Dimer Carbamates Than By The Trioxane Antimalarial Drug Artemeth...

by Conyers, Ryan C., Mazzone, Jennifer R., Siegler, Maxime A., Tripathi, Abhai K., Sullivan, David J., Mott, Bryan T., Posner, Gary H.
Published 2014

Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site

by Kasbekar, Monica, Fischer, Gerhard, Mott, Bryan T., Yasgar, Adam, Hyvönen, Marko, Boshoff, Helena I. M., Abell, Chris, Barry, Clifton E., Thomas, Craig J.
Published in Proc Natl Acad Sci U S A (2016)

Malaria-Infected Mice are Completely Cured by One 6 mg/kg Oral Dose of a New Monomeric Trioxane Sulfide Combined with Mefloquine

by Slack, Rachel D., Mott, Bryan T., Woodard, Lauren E., Triphati, Abhai, Sullivan, David, Nenortas, Elizabeth, Girdwood, Sonya C. T., Shapiro, Theresa A., Posner, Gary H.
Published 2011

Quantitative Analyses of Aggregation, Autofluorescence, and Reactivity Artifacts in a Screen for Inhibitors of a Thiol Protease

by Jadhav, Ajit, Ferreira, Rafaela S., Klumpp, Carleen, Mott, Bryan T., Austin, Christopher P., Inglese, James, Thomas, Craig J., Maloney, David J., Shoichet, Brian K., Simeonov, Anton
Published 2010

Potent and Selective Small Molecule Inhibitors of Specific Isoforms of Cdc2-like Kinases (Clk) and Dual Specificity Tyrosine-Phosphorylation-Regulated Kinases (Dyrk)

by Rosenthal, Andrew S., Tanega, Cordelle, Shen, Min, Mott, Bryan T., Bougie, James M., Nguyen, Dac-Trung, Misteli, Tom, Auld, Douglas S., Maloney, David J., Thomas, Craig J.
Published 2011

In vitro Screening of Compounds against Laboratory and Field Isolates of Human Hookworm Reveals Quantitative Differences in Anthelmintic Susceptibility

by Treger, Rebecca S., Otchere, Joseph, Keil, Martin F., Quagraine, Josephine E., Rai, Ganesha, Mott, Bryan T., Humphries, Debbie L., Wilson, Michael, Cappello, Michael, Vermeire, Jon J.
Published 2014

Complementarity Between a Docking and a High-Throughput Screen in Discovering New Cruzain Inhibitors

by Ferreira, Rafaela S., Simeonov, Anton, Jadhav, Ajit, Eidam, Oliv, Mott, Bryan T., Keiser, Michael J., McKerrow, James H., Maloney, David J., Irwin, John J., Shoichet, Brian K.
Published 2010