Artemisinin-Derived Dimer Phosphate Esters as Potent Anti-Cytomegalovirus (Anti-CMV) and Anti-Cancer Agents: A Structure-Activity Study

We recently reported the anti-cancer and anti-cytomegalovirus (CMV) activity of artemisinin-derived trioxane diphenylphosphate dimer 838. To probe the relationship between chemical structure and anti-CMV and anti-cancer activities, we now report synthesis and evaluation of a series of eight new dime...

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Detalhes bibliográficos
Main Authors: Mott, Bryan T., He, Ran, Chen, Xiaochun, Fox, Jennifer M., Civin, Curt I., Arav-Boger, Ravit, Posner, Gary H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685872/
https://ncbi.nlm.nih.gov/pubmed/23673218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.04.027
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