Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs

Artemisinins, endoperoxide-containing molecules, best known as antimalarials, have potent antineoplastic activity. The established antimalarial, artesunate (AS), and the novel artemisinin-derived trioxane diphenylphosphate dimer 838 (ART-838) inhibited growth of all 23 tested acute leukemia cell lin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Oncotarget
मुख्य लेखकों: Fox, Jennifer M., Moynihan, James R., Mott, Bryan T., Mazzone, Jennifer R., Anders, Nicole M., Brown, Patrick A., Rudek, Michelle A., Liu, Jun O., Arav-Boger, Ravit, Posner, Gary H., Civin, Curt I., Chen, Xiaochun
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2016
विषय:
Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872784/
https://ncbi.nlm.nih.gov/pubmed/26771236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6896
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