Quantitative High-Throughput Screening Using a Coincidence Reporter Biocircuit

Por Schuck, Brittany W., MacArthur, Ryan, Inglese, James
Publicado no Curr Protoc Neurosci (2017)

Identification of Drug Modulators Targeting Gene-Dosage Disease CMT1A

Por Jang, Sung-Wook, Lopez-Anido, Camila, MacArthur, Ryan, Svaren, John, Inglese, James
Publicado em 2012

Comparison of Bioluminescent Kinase Assays Using Substrate Depletion and Product Formation

Por Tanega, Cordelle, Shen, Min, Mott, Bryan T., Thomas, Craig J., MacArthur, Ryan, Inglese, James, Auld, Douglas S.
Publicado em 2009

Profile of the GSK Published Protein Kinase Inhibitor Set Across ATP-Dependent and-Independent Luciferases: Implications for Reporter-Gene Assays

Por Dranchak, Patricia, MacArthur, Ryan, Guha, Rajarshi, Zuercher, William J., Drewry, David H., Auld, Douglas S., Inglese, James
Publicado em 2013

Monitoring compound integrity with cytochrome P450 assays and qHTS

Por MacArthur, Ryan, Leister, William, Veith, Henrike, Shinn, Paul, Southall, Noel, Austin, Christopher P., Inglese, James, Auld, Douglas S.
Publicado em 2009

A Miniaturized Glucocorticoid Receptor Translocation Assay using Enzymatic Fragment Complementation Evaluated with qHTS

Por Zhu, Ping Jun, Zheng, Wei, Auld, Douglas S., Jadhav, Ajit, MacArthur, Ryan, Olson, Keith R., Peng, Kun, Dotimas, Hyna, Austin, Christopher P., Inglese, James
Publicado em 2008

A Quantitative High-Throughput Screen for Modulators of IL-6 Signaling: A Model for Interrogating Biological Networks using Chemical Libraries

Por Johnson, Ronald L., Huang, Ruili, Jadhav, Ajit, Southall, Noel, Wichterman, Jennifer, MacArthur, Ryan, Xia, Menghang, Bi, Kun, Printen, John, Austin, Christopher P., Inglese, James
Publicado em 2009

Titration-based screening for evaluation of natural product extracts: identification of an aspulvinone family of luciferase inhibitors

Por Cruz, Patricia G., Auld, Douglas S., Schultz, Pamela J., Lovell, Scott, Battaile, Kevin P., MacArthur, Ryan, Shen, Min, Tamayo-Castillo, Giselle, Inglese, James, Sherman, David H.
Publicado em 2011

Genome Editing-Enabled HTS Assays Expand Drug Target Pathways for Charcot–Marie–Tooth Disease

Por Inglese, James, Dranchak, Patricia, Moran, John J., Jang, Sung-Wook, Srinivasan, Rajini, Santiago, Yolanda, Zhang, Lei, Guha, Rajarshi, Martinez, Natalia, MacArthur, Ryan, Cost, Gregory J., Svaren, John
Publicado no ACS Chem Biol (2014)

Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases

Por Yu, Hao, Dranchak, Patricia, Li, Zhiru, MacArthur, Ryan, Munson, Matthew S., Mehzabeen, Nurjahan, Baird, Nathan J., Battalie, Kevin P., Ross, David, Lovell, Scott, Carlow, Clotilde K. S., Suga, Hiroaki, Inglese, James
Publicado no Nat Commun (2017)

Identification of Pregnane X Receptor Ligands Using Time-Resolved Fluorescence Resonance Energy Transfer and Quantitative High-Throughput Screening

Por Shukla, Sunita J., Nguyen, Dac-Trung, MacArthur, Ryan, Simeonov, Anton, Frazee, William J., Hallis, Tina M., Marks, Bryan D., Singh, Upinder, Eliason, Hildegard C., Printen, John, Austin, Christopher P., Inglese, James, Auld, Douglas S.
Publicado em 2009

Actinoramide A Identified as a Potent Antimalarial from Titration-based Screening of Marine Natural Product Extracts

Por Cheng, Ken Chih-Chien, Cao, Shugeng, Raveh, Avi, MacArthur, Ryan, Dranchak, Patricia, Chlipala, George, Okoneski, Matthew T., Guha, Rajarshi, Eastman, Richard T., Yuan, Jing, Schultz, Pamela J., Su, Xin-zhuan, Tamayo-Castillo, Giselle, Matainaho, Teatulohi, Clardy, Jon, Sherman, David H., Inglese, James
Publicado no J Nat Prod (2015)

Discovery of new antimalarial chemotypes through chemical methodology and library development

Por Brown, Lauren E., Chih-Chien Cheng, Ken, Wei, Wan-Guo, Yuan, Pingwei, Dai, Peng, Trilles, Richard, Ni, Feng, Yuan, Jing, MacArthur, Ryan, Guha, Rajarshi, Johnson, Ronald L., Su, Xin-zhuan, Dominguez, Melissa M., Snyder, John K., Beeler, Aaron B., Schaus, Scott E., Inglese, James, Porco, John A.
Publicado em 2011