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Quantitative High-Throughput Screening Using a Coincidence Reporter Biocircuit
Reporter-biased artifacts, compounds that interact directly with the reporter enzyme used in a high-throughput screening (HTS) assay, and not the biology or pharmacology being interrogated, are now widely recognized to reduce the efficiency and quality of HTS used for chemical probe and therapeutic...
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| 出版年: | Curr Protoc Neurosci |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5510169/ https://ncbi.nlm.nih.gov/pubmed/28398644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpns.27 |
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