Identification of Pregnane X Receptor Ligands Using Time-Resolved Fluorescence Resonance Energy Transfer and Quantitative High-Throughput Screening

The human pregnane X nuclear receptor (PXR) is a xenobiotic-regulated receptor that is activated by a range of diverse chemicals, including antibiotics, antifungals, glucocorticoids, and herbal extracts. PXR has been characterized as an important receptor in the metabolism of xenobiotics due to indu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Shukla, Sunita J., Nguyen, Dac-Trung, MacArthur, Ryan, Simeonov, Anton, Frazee, William J., Hallis, Tina M., Marks, Bryan D., Singh, Upinder, Eliason, Hildegard C., Printen, John, Austin, Christopher P., Inglese, James, Auld, Douglas S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2009
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116688/
https://ncbi.nlm.nih.gov/pubmed/19505231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2009.193
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