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Identification of Drug Modulators Targeting Gene-Dosage Disease CMT1A
The structural integrity of myelin formed by Schwann cells in the peripheral nervous system (PNS) is required for proper nerve conduction and is dependent on adequate expression of myelin genes including peripheral myelin protein 22 (PMP22). Consequently, excess PMP22 resulting from its genetic dupl...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401360/ https://ncbi.nlm.nih.gov/pubmed/22530759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300048d |
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