A sterically encumbered photoredox catalyst enables the unified synthesis of the classical lignan family of natural products

le Alfonzo, Edwin, Beeler, Aaron B.
Foilsithe in Chem Sci (2019)

Synthesis of Azaphilone-Based Chemical Libraries

le Achard, Mathieu, Beeler, Aaron B., Porco, John A.
Foilsithe 2012

One-pot synthesis of epoxides from benzyl alcohols and aldehydes

le Alfonzo, Edwin, Mendoza, Jesse W L, Beeler, Aaron B
Foilsithe in Beilstein J Org Chem (2018)

1,2,3,4-Tetrahydro-1,5-naphthyridines and related heterocyclic scaffolds: Exploration of suitable chemistry for library development

le Woo, Grace H. C., Beeler, Aaron B., Snyder, John K.
Foilsithe 2007

Catalytic Enantioselective Alkylative Dearomatization-Annulation: Total Synthesis and Absolute Configuration Assignment of Hyperibone K

le Qi, Ji, Beeler, Aaron B., Zhang, Qiang, Porco, John A.
Foilsithe 2010

A Photochemical Flow Reactor for Large Scale Syntheses of Aglain and Rocaglate Natural Product Analogs

le Yueh, Han, Gao, Qiwen, Porco, John A., Beeler, Aaron B.
Foilsithe in Bioorg Med Chem (2017)

Synthesis of a novel chemotype via sequential metal-catalyzed cycloisomerizations

le Leng, Bo, Chichetti, Stephanie, Su, Shun, Beeler, Aaron B, Porco, John A
Foilsithe 2012

Tandem Processes Identified from Reaction Screening: Nucleophilic Addition to Aryl N-Phosphinylimines Employing La(III)-TFAA activation

le Kinoshita, Hidenori, Ingham, Oscar J., Ong, Winnie W., Beeler, Aaron B., Porco, John A.
Foilsithe 2010

Synthesis and Reactivity of Bicyclo[3.2.1]Octanoid- Derived Cyclopropanes

le Goodell, John R., Poole, Jennifer L., Beeler, Aaron B., Aubé, Jeffrey, Porco, John A.
Foilsithe 2011

Multidimensional Screening and Methodology Development for Condensations Involving Complex 1,2-Diketones

le Goodell, John R., Leng, Bo, Snyder, Tracy K., Beeler, Aaron B., Porco, John A.
Foilsithe 2010

Reaction Discovery Employing Macrocycles: Transannular Cyclizations of Macrocyclic Bis-Lactams

le Han, Chong, Rangarajan, Sathish, Voukides, Alicia C, Beeler, Aaron B., Johnson, Richard, Porco, John A.
Foilsithe 2009

Remodeling of the Natural Product Fumagillol Employing a Reaction Discovery Approach

le Balthaser, Bradley R., Maloney, Meghan C., Beeler, Aaron B., Porco, John A., Snyder, John K.
Foilsithe 2011

Multidimensional Reaction Screening for Photochemical Transformations as a Tool for Discovering New Chemotypes

le Martin, Véronique I., Goodell, John R., Ingham, Oscar J., Porco, John A., Beeler, Aaron B.
Foilsithe 2014

Fine-tuning of macrophage activation using synthetic rocaglate derivatives

le Bhattacharya, Bidisha, Chatterjee, Sujoy, Devine, William G., Kobzik, Lester, Beeler, Aaron B., Porco, John A., Kramnik, Igor
Foilsithe in Sci Rep (2016)

Identification of Anti-prion Compounds using a Novel Cellular Assay

le Imberdis, Thibaut, Heeres, James T., Yueh, Han, Fang, Cheng, Zhen, Jessie, Rich, Celeste B., Glicksman, Marcie, Beeler, Aaron B., Harris, David A.
Foilsithe in J Biol Chem (2016)

A Time-Resolved Fluorescence–Resonance Energy Transfer Assay for Identifying Inhibitors of Hepatitis C Virus Core Dimerization

le Kota, Smitha, Scampavia, Louis, Spicer, Timothy, Beeler, Aaron B., Takahashi, Virginia, Snyder, John K., Porco, John A., Hodder, Peter, Strosberg, Arthur Donny
Foilsithe 2010

Development of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffolds

le Goodell, John R., McMullen, Jonathan P., Zaborenko, Nikolay, Maloney, Jason R., Ho, Chuan-Xing, Jensen, Klavs F., Porco, John A., Beeler, Aaron B.
Foilsithe 2009

Development of a Potent and Selective HDAC8 Inhibitor

le Ingham, Oscar J., Paranal, Ronald M., Smith, William B., Escobar, Randolph A., Yueh, Han, Snyder, Tracy, Porco, John A., Bradner, James E., Beeler, Aaron B.
Foilsithe in ACS Med Chem Lett (2016)

Identification of Novel Epoxide Inhibitors of Hepatitis C Virus Replication Using a High-Throughput Screen

le Peng , Lee F., Kim, Sun Suk, Matchacheep, Sirinya, Lei, Xiaoguang, Su, Shun, Lin, Wenyu, Runguphan, Weerawat, Choe, Won-Hyeok, Sakamoto, Naoya, Ikeda, Masanori, Kato, Nobuyuki, Beeler, Aaron B., Porco, John A., Schreiber, Stuart L., Chung, Raymond T.
Foilsithe 2007

Discovery of new antimalarial chemotypes through chemical methodology and library development

le Brown, Lauren E., Chih-Chien Cheng, Ken, Wei, Wan-Guo, Yuan, Pingwei, Dai, Peng, Trilles, Richard, Ni, Feng, Yuan, Jing, MacArthur, Ryan, Guha, Rajarshi, Johnson, Ronald L., Su, Xin-zhuan, Dominguez, Melissa M., Snyder, John K., Beeler, Aaron B., Schaus, Scott E., Inglese, James, Porco, John A.
Foilsithe 2011