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1,2,3,4-Tetrahydro-1,5-naphthyridines and related heterocyclic scaffolds: Exploration of suitable chemistry for library development

The chemistry of 1,2,3,4-tetrahydro-1,5-naphthyridines and 2,3,4,5-tetrahydro-1H-pyrido[3,2-b]azepines has been explored with the goal of discovering reactions at N1 suitable for library development. Epoxide openings, palladium-catalyzed N-arylations, DEPBT-promoted acylations, and urea formation th...

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Detalhes bibliográficos
Main Authors: Woo, Grace H. C., Beeler, Aaron B., Snyder, John K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2608727/
https://ncbi.nlm.nih.gov/pubmed/19112520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.04.003
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