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Identification of Anti-prion Compounds using a Novel Cellular Assay
Prion diseases are devastating neurodegenerative disorders with no known cure. One strategy for developing therapies for these diseases is to identify compounds that block conversion of the cellular form of the prion protein (PrP(C)) into the infectious isoform (PrP(Sc)). Most previous efforts to di...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5207084/ https://ncbi.nlm.nih.gov/pubmed/27803163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745612 |
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