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Identification of Anti-prion Compounds using a Novel Cellular Assay
Prion diseases are devastating neurodegenerative disorders with no known cure. One strategy for developing therapies for these diseases is to identify compounds that block conversion of the cellular form of the prion protein (PrP(C)) into the infectious isoform (PrP(Sc)). Most previous efforts to di...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5207084/ https://ncbi.nlm.nih.gov/pubmed/27803163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.745612 |
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